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MitoTools

MitoTools are a libary of FP-tagged components of the mitochondrial calcium uptake machinery. These fluorescent tools can be used to study the architecture and functioning of mitochondrial calcium uniport on the single cell level. E.g. FRET imaging between MICU1-CFP and MICU1-YFP was used to investigate the calcium dependent rearrangment of MICU1 oligomers. This is an essential step in the activation of MCU (see reference).

Here we provide the most important constituents of the MCU machinery as FP-tagged constructs in form of ready-to-use plasmid DNA

EMRE Constructs

hEMRE untagged

 150.00 excl.VAT

hEMRE-Citrine

hEMRE-Citrine

 150.00 excl.VAT

EMRE Constructs

hEMRE-ECFP

 150.00 excl.VAT

EMRE Constructs

hEMRE-mCherry

 150.00 excl.VAT

hLETM1 untagged

hLETM1 untagged

 150.00 excl.VAT

hLETM1-mCherry

hLETM1-mCherry

 150.00 excl.VAT

hMCU -Citrine

hMCU -Citrine

 150.00 excl.VAT

hMCUE257Q-mCherry

hMCU E257Q-mCherry

 150.00 excl.VAT

hMCU untagged

hMCU untagged

 150.00 excl.VAT

hMCU-ECFP

hMCU-ECFP

 150.00 excl.VAT
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hMCU-FRET

hMCU-FRET

 250.00 excl.VAT

hMCUb -Citrine

hMCUb -Citrine

 150.00 excl.VAT